严肃的探索抗衰老药

在政府实验室和其他地方,科学家们正在寻找一种能够延长寿命和青春活力的药物。热量限制研究正在为此指明方向

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2-Deoxy-D-Glucose Feeding in Rats Mimics Physiological Effects of Caloric Restriction. Mark A. Lane, George S. Roth and Donald K. Ingram in Journal of Anti-Aging Medicine, Vol. 1, No. 4, pages 327¿337; Winter 1998.

Caloric Restriction and Aging. Richard Weindruch in 大众科学, Vol. 274, No. 1, pages 46¿52; January 1996.

Caloric Restriction in Primates and Relevance to Humans. George S. Roth, Donald K. Ingram and Mark A. Lane in Annals of the New York Academy of Sciences, Vol. 928, pages 305¿315; 2001.

MARK A. LANE, DONALD K. INGRAM and GEORGE S. ROTH researched caloric restriction together for many years at the National Institute on Aging of the National Institutes of Health. Lane, who in March became a project manager at Merck and Co., in Rahway, N.J., continues to collaborate with Ingram and Roth as a guest investigator at the NIA. Ingram is chief of the Behavioral Neuroscience Section at the institute's Laboratory of Neurosciences. Roth, who spent nearly 30 years as a full-time researcher at the NIA, is now a senior guest scientist there. He is also chief executive officer of GeroTech, a new biotechnology venture devoted to anti-aging strategies.

More by Mark A. Lane, Donald K. Ingram and George S. Roth
大众科学 Magazine Vol 287 Issue 2This article was originally published with the title “The Serious Search for an Anti-Aging Pill” in 大众科学 Magazine Vol. 287 No. 2 ()
doi:10.1038/scientificamerican082002-7iLwnwurUmFop3N3W6x0sx
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