药物大幅降低心脏病发作风险

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科学家在治疗心脏病方面迈出了重要一步。新的研究表明,对于经历急性胸痛的患者,在标准疗法中加入获得许可的血液稀释药物氯吡格雷,可以将死亡、心脏病发作和中风的风险降低近 20%。这项研究的结果于周一在美国心脏病学会于佛罗里达州奥兰多举行的会议上公布,表明该药物每年可以挽救数千名美国人的生命。

在一项针对 28 个国家超过 12,500 名患者的研究中,安大略省汉密尔顿市麦克马斯特大学的团队负责人 Salim Yusuf 及其同事检查了氯吡格雷对一种危及生命的疾病——急性冠状动脉综合征的影响。一半的参与者在标准疗法的基础上每天服用一剂氯吡格雷,另一半则仅接受标准疗法。研究小组发现,氯吡格雷组的心脏病发作减少了 23%,中风减少了 15%。

氯吡格雷由赛诺菲-圣德拉堡以波立维 (Plavix) 的名义销售,由百时美施贵宝以 Iscover 的名义销售,已使用一段时间以帮助预防血管成形术后的血栓,但新的结果可能会使其成为所有心脏病发作患者的标准。“这是自阿司匹林以来最好的消息,”哈佛医学院医学助理教授克里斯托弗·P·坎农在《纽约时报》上评论道。“这真是一种名副其实的超级阿司匹林。”

Kate Wong is an award-winning science writer and senior editor at 大众科学 focused on evolution, ecology, anthropology, archaeology, paleontology and animal behavior. She is fascinated by human origins, which she has covered for more than 25 years. Recently she has become obsessed with birds. Her reporting has taken her to caves in France and Croatia that Neandertals once called home, to the shores of Kenya's Lake Turkana in search of the oldest stone tools in the world, to Madagascar on an expedition to unearth ancient mammals and dinosaurs, to the icy waters of Antarctica, where humpback whales feast on krill, and on a "Big Day" race around the state of Connecticut to find as many bird species as possible in 24 hours. Kate is co-author, with Donald Johanson, of Lucy's Legacy: The Quest for Human Origins. She holds a bachelor of science degree in biological anthropology and zoology from the University of Michigan. Follow Wong on X (formerly Twitter) @katewong

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