偏头痛与脑损伤有关

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一项新研究的结果表明,一些偏头痛患者可能面临脑损伤风险增加。这些发现今天发表在《美国医学会杂志》上,可能表明这种使人衰弱的头痛在某些情况下是一种进行性脑疾病。

这项研究调查了295名年龄在30至60岁之间的患有偏头痛的荷兰成年人,其中一些人有视觉障碍(或先兆,用技术术语来说),另一些人没有,以及140名无偏头痛的对照组受试者。研究人员使用磁共振成像技术,由荷兰莱顿大学医学中心的马克·C·克鲁伊特领导,扫描了参与者的大脑,以寻找脑梗塞(由于缺氧而死亡的组织,即血栓阻塞动脉的结果)和白质病变。他们发现,无先兆偏头痛患者的梗塞风险是对照组的七倍;有先兆偏头痛患者的风险约为对照组的13倍,对于每月发作一次或以上的受试者,风险增加近16倍。

在随刊评论中,阿尔伯特·爱因斯坦医学院的理查德·B·利普顿和朱莉·潘写道,偏头痛“不应仅仅被概念化为一种发作性疾病,而应被概念化为一种慢性发作性和有时慢性进行性疾病。” 他们说,随着思维方式的转变,治疗策略也可能发生变化。“如果克鲁伊特等人证实的脑损伤具有显着的临床相关性,那么预防脑损伤的积累可能成为治疗的额外目标。”

Kate Wong is an award-winning science writer and senior editor at 大众科学 focused on evolution, ecology, anthropology, archaeology, paleontology and animal behavior. She is fascinated by human origins, which she has covered for more than 25 years. Recently she has become obsessed with birds. Her reporting has taken her to caves in France and Croatia that Neandertals once called home, to the shores of Kenya's Lake Turkana in search of the oldest stone tools in the world, to Madagascar on an expedition to unearth ancient mammals and dinosaurs, to the icy waters of Antarctica, where humpback whales feast on krill, and on a "Big Day" race around the state of Connecticut to find as many bird species as possible in 24 hours. Kate is co-author, with Donald Johanson, of Lucy's Legacy: The Quest for Human Origins. She holds a bachelor of science degree in biological anthropology and zoology from the University of Michigan. Follow Wong on X (formerly Twitter) @katewong

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